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Welcome to the GPCL
The GPCL is a resource of the Clinical and Translational Science Institute (ctsi). For an overview of the GPCL please see our introduction.

 
Bioinformatics Analysis Core
The Bioinformatics Analysis Core (BAC) of the Genomics and Proteomics Core Laboratories provides data analysis services for a broad range of data types. We are available to consult and participate in basic and clinical study design, including patient accrual algorithms and multivariable case/control selection. 		-Details
 
DNA/RNA Extraction
The specimen processing and banking laboratories have extensive RNA/DNA extraction experience for dozens of tissue types and species. Extraction can be performed in standard or high throughput formats. Whole Genome Amplification is also available. Secure specimen banking facilities are available.		 -DNA
-RNA
-Whole Genome Amp.
DNA Analysis
We offer genetic and genomic analyses for a variety of applications. Sequencing is available in standard and high throughput formats. The choice of Taqman, Affymetrix or Illumina based SNP assay platforms is based on project goals and throughput needs.		 -Sequencing
-SNP Genotyping
-DNA Methylation
RNA Analysis
Our MicroArray and Taqman Real Time PCR offerings allow investigators to obtain gene expression data from a flexible array of formats. Full service is available for all offerings including Affymetrix and Illumina gene expression Array products. 		-Microarray Analysis
-Realtime PCR
-miRNA Analysis
Protein Profiling
Protein profiling and separations technologies are often customized based on the needs of each project. Standardized processes include traditional and Cy-dye (DiGE) based 2 dimensional (2D) gel electrophoresis (PAGE). Nano flow Mudpit analyses are available in MDLC MALDI and ion trap methods.		 -2D Gel
-Nano LC Maldi
-Nano LC ESI
Protein ID
Protein identification and characterization processes include Peptide Mass Fingerprinting (PMF), de novo sequencing, Post Translational Modification (PTM) analysis and many other chemical and mass spectrometry techniques.		 -PMF
-de novo Sequencing
-PTM
Affiliated Services
  Peptide Synthesis Core
The Peptide Synthesis Core provides accessible, economical, comprehensive, and state-of-the-art synthetic peptide production services. These services include peptide design, synthesis, purification, and quality control, including certified peptides for use in phase I and phase II clinical trials.
 

-Cytogenetics Facility
 
NEWS

Bruker Apex Qe 12 Tesla Fourier Transform Mass Spectrometer (Apex Qe FTMS): Protein Structure & Post-Translational Modification Analysis now available at the GPCL
click to view FTMS flyer

SNP Platforms available at the GPCL
click to view SNP flyer

Former GPCL seminar
Title: Next-Generation Sequencing with the Roche GS-FLX
With special guest speaker Elodie Ghedin, PhD
Presentation files are avaiable here:  1,  2,  3

Roche (454) GS-FLX:
Next Generation Sequencing now available at the GPCL
click to view FLX flyer

GPCL BAC Announcement:
The Clinical and Translational Science Institute and the Office of Research, Health Sciences are pleased to announce the formation of the Bioinformatics Analysis Core within the GPCL.
Read more


miRNA Posters:
miRNA realtime PCR evaluation
miRNA extraction evaluation